Skip to content
Hindi News, हिंदी समाचार, Samachar, Breaking News, Latest Khabar – Pratirodh

Hindi News, हिंदी समाचार, Samachar, Breaking News, Latest Khabar – Pratirodh

Primary Menu Hindi News, हिंदी समाचार, Samachar, Breaking News, Latest Khabar – Pratirodh

Hindi News, हिंदी समाचार, Samachar, Breaking News, Latest Khabar – Pratirodh

  • Home
  • Newswires
  • Politics & Society
  • The New Feudals
  • World View
  • Arts And Aesthetics
  • For The Record
  • About Us
  • Featured

Covaxin ‘Effectively Neutralises’ Delta Variant: US NIH

Jun 30, 2021 | Pratirodh Bureau

FILE PHOTO: A medic fills a syringe with Covaxin before administering it to a health worker at the Gujarat Medical Education and Research Society in Ahmedabad

India’s Covaxin, developed by Bharat Biotech in collaboration with the Indian Council of Medical Research, effectively neutralises both Alpha and Delta variants of coronavirus, the US’ National Institute of Health has said.

The NIH said results of two studies of blood serum from people who had received Covaxin suggest that the vaccine generates antibodies that effectively neutralise the B.1.1.7 (Alpha) and B.1.617 (Delta) variants of SARS-CoV-2, first identified in the UK and India, respectively.

The top American health research institute, which has a history of strong scientific collaboration with India, also said that an adjuvant developed with funding from it has contributed to the success of the highly efficacious Covaxin, which has been administered to roughly 25 million people till date in India and elsewhere.

Adjuvants are substances formulated as part of a vaccine to boost immune responses and enhance a vaccine’s effectiveness.

Covaxin comprises a disabled form of SARS-CoV-2 that cannot replicate but still stimulates the immune system to make antibodies against the virus. Published results from a phase 2 trial of the vaccine indicate that it is safe and well tolerated, the NIH said, adding that safety data from a phase 3 trial of Covaxin will become available later this year.

“Meanwhile, unpublished interim results from the phase 3 trial indicate that the vaccine has 78 per cent efficacy against symptomatic disease, 100 per cent efficacy against severe COVID-19, including hospitalisation, and 70 per cent efficacy against asymptomatic infection with SARS-CoV-2, the virus that causes COVID-19,” it said.

“The results from two studies of blood serum from people who had received Covaxin suggest that the vaccine generates antibodies that effectively neutralise the B.1.1.7 (Alpha) and B.1.617 (Delta) variants of SARS-CoV-2, first identified in the UK and India, respectively,” the NIH said.

Ending a global pandemic requires a global response, said Anthony S Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), part of NIH.

“I am pleased that a novel vaccine adjuvant developed in the US with NIAID support is part of an efficacious COVID-19 vaccine available to people in India,” he said.

The adjuvant used in Covaxin, Alhydroxiquim-II, was discovered and tested in a laboratory by the biotech company ViroVax LLC of Lawrence, Kansas with support from the NIAID Adjuvant Development Program.

Alhydroxiquim-II is the first adjuvant in an authorised vaccine against an infectious disease to activate receptors TLR7 and TLR8 that play a vital role in the immune response to viruses.

In addition, the alum in Alhydroxiquim-II stimulates the immune system to search for an invading pathogen. Molecules that activate TLR receptors stimulate the immune system powerfully, but the side effects of Alhydroxiquim-II are mild, the NIH said.

According to the NIH, the NIAID Adjuvant Program has supported the research of the founder and chief executive officer of ViroVax, Sunil David, MD, PhD, since 2009. His work has focused on searching for novel molecules that activate innate immune receptors and developing them as vaccine adjuvants.

The collaboration between Dr David and Bharat Biotech International Ltd. of Hyderabad was initiated during a 2019 meeting in India coordinated by the NIAID Office of Global Research under the auspices of NIAID’s Indo-US Vaccine Action Program.

A delegation of five NIAID-funded adjuvant investigators, including Dr David; two members of the NIAID Division of Allergy, Immunology, and Transplantation; and the NIAID India representative, visited four leading biotechnology companies to learn about their work and discuss potential collaborations.

The delegation also attended a consultation in New Delhi co-organised by NIAID and India’s Department of Biotechnology and hosted by India’s National Institute of Immunology.

Among the scientific collaborations sparked by these activities, Bharat Biotech signed a licensing agreement with Dr David to use Alhydroxiquim-II in their candidate vaccines. This license was expanded during the COVID-19 pandemic to include Covaxin, which has received Emergency Use Authorisation in India and more than a dozen other countries.

“The company conducted extensive safety studies of Alhydroxiquim-II and undertook the complex process of scaling up production of the adjuvant under Good Manufacturing Practice standards. Bharat Biotech expects to produce an estimated 700 million doses of Covaxin by the end of 2021,” the NIH said.

Tags: Covaxin, COVID-19, Delta Covid variant, Indian Council of Medical Research, National Institute of Allergy and Infectious Diseases, NIAID, Pratirodh, US National Institute of Health

Continue Reading

Previous Online Posts Falsely Claim Covid-19 Shots Damage Blood Cells
Next Why ‘Work From Home’ Works So Well For So Many

More Stories

  • Featured

26% Of World Lacks Clean Drinking Water, 46% Sanitation: UN

3 hours ago Pratirodh Bureau
  • Featured

‘Severe Consequences’ Of Further Warming In Himalayas: IPCC

5 hours ago Pratirodh Bureau
  • Featured

NIA Arrests Kashmiri Journalist, Mufti Says This Is Misuse Of UAPA

21 hours ago Shalini

Recent Posts

  • 26% Of World Lacks Clean Drinking Water, 46% Sanitation: UN
  • ‘Severe Consequences’ Of Further Warming In Himalayas: IPCC
  • NIA Arrests Kashmiri Journalist, Mufti Says This Is Misuse Of UAPA
  • BJP Is Just A Tenant, Not Owner Of Democracy: Congress
  • Livable Future Possible If Drastic Action Taken This Decade: IPCC Report
  • Significant Human Rights Issues In India, Finds US Report
  • Bhopal Gas Tragedy: NGOs Upset Over Apex Court Ruling
  • Kisan Mahapanchayat: Thousands Of Farmers Gather In Delhi
  • Nations Give Nod To Key UN Science Report On Climate Change
  • AI: The Real Danger Lies In Anthropomorphism
  • BJP, Like Cong, Will Be Finished For Misusing Central Agencies: Akhilesh
  • J&K Admin Incompetent: Omar Abdullah Over Conman Issue
  • Oxygen Loss In Oceans Predicted To Threaten Global Marine Ecosystems
  • Ukraine War Crime Allegations: Arrest Warrant Against Putin
  • COVID, Bird Flu – Why We Are Seeing So Many Viruses Emerge
  • IMSD Takes On Right Wing Muslims Ridiculing LGBTQIA+ Community
  • Nothing Remotely Anti-National About Rahul’s Comments: Tharoor
  • Great Depression, Global Recession Repeat: No Lessons Learnt?
  • Why We Can’t Rely On Air Conditioning To Keep Us Cool
  • Iranian Child Detainees Face Torture In Brutal Protest Crackdown

Search

Main Links

  • Home
  • Newswires
  • Politics & Society
  • The New Feudals
  • World View
  • Arts And Aesthetics
  • For The Record
  • About Us

Related Stroy

  • Featured

26% Of World Lacks Clean Drinking Water, 46% Sanitation: UN

3 hours ago Pratirodh Bureau
  • Featured

‘Severe Consequences’ Of Further Warming In Himalayas: IPCC

5 hours ago Pratirodh Bureau
  • Featured

NIA Arrests Kashmiri Journalist, Mufti Says This Is Misuse Of UAPA

21 hours ago Shalini
  • Featured

BJP Is Just A Tenant, Not Owner Of Democracy: Congress

21 hours ago Pratirodh Bureau
  • Featured

Livable Future Possible If Drastic Action Taken This Decade: IPCC Report

1 day ago Pratirodh Bureau

Recent Posts

  • 26% Of World Lacks Clean Drinking Water, 46% Sanitation: UN
  • ‘Severe Consequences’ Of Further Warming In Himalayas: IPCC
  • NIA Arrests Kashmiri Journalist, Mufti Says This Is Misuse Of UAPA
  • BJP Is Just A Tenant, Not Owner Of Democracy: Congress
  • Livable Future Possible If Drastic Action Taken This Decade: IPCC Report
Copyright © All rights reserved. | CoverNews by AF themes.